Heidelberg, 19 August 2019.
The latest paper from the research group at the David J Apple Lab has been accepted for future publication (in December later this year) in the influential American Journal of Ophthalmology,
The Effect of a Spectral Filter on Visual Quality in Patients with an Extended-Depth-Of-Focus Intraocular Lens
Grzegorz Łabuz, Gerd U. Auffarth, Aydin Özen, Thomas J.T.P. Van Den Berg, Timur M. Yildirim, Hyeck-Soo Son, and Ramin Khoramnia, American Journal of Ophthalmology (2019) Volume 208, December 2019, Pages 56-63, https://doi.org/10.1016/j.ajo.2019.07.001
Dr Łabuz summarised the research work,
We know that diffractive IOLs show wavelength dependence, but until now, this had not been assessed in vivo. So we examined 12 patients (23 eyes) who had received a Symfony lens (Johnson & Johnson Vision) – we measured them monocularly under red and white light at far, intermediate, and near distances. The patients’ corrected distance visual acuity (CDVA), distance-corrected intermediate visual acuity (DCIVA), and distance corrected near visual acuity (DCNVA) were all assessed. Contrast sensitivity was examined at several spatial frequencies. Then we looked in the laboratory, at the IOL’s modulation transfer function under different spectral conditions. We found,
- CDVA was comparable under red and white light. DCIVA and DCNVA were significantly better under white light by 0.06 and 0.09, respectively.
- Contrast sensitivity was slightly better with a red filter at a far distance but was worse at an intermediate distance, although differences were significant only at 1 frequency.
- Near contrast sensitivity was better under polychromatic than red light, which was significant at 3 frequencies.
- The in vitro analysis confirmed Symfony’s wavelength dependence: performance was improved at a far distance but was worse at intermediate and near distances
Prof Auffarth added that these findings have clinical relevance. Symfony’s spectral dependence affects visual acuity and contrast sensitivity. Although the red filter did not improve distance vision, it caused visual deterioration at the
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